Tag:

osteoarthritis

Latest Headlines

Latest Headlines

Xenon's Teva-partnered pain drug flunks a test in osteoarthritis

Xenon Pharmaceuticals' Teva-partnered treatment for osteoarthritis pain missed its goals in a Phase IIb trial, a failure the biotech believes won't derail the drug's development in other indications.

UPDATED: Startup Moximed gets $33M to gain FDA approval of early stage osteoarthritis knee implant

Moximed anticipates that its KineSpring System will prove useful for osteoarthritis sufferers as a first surgical step offered before arthroplasty. In support of its quest, the company has raised $33 million that it expects will be sufficient to gain FDA approval for the system.

Ampio routed as lead osteoarthritis drug flunks a PhIII test

Shares of Ampio Pharmaceuticals were crushed this morning after the biotech acknowledged that its lead drug flunked a Phase III test for osteoarthritis. And the news comes just days after one of its drug subsidiaries was absorbed into a new biotech that will be called Aytu.

Developer of injectable osteoarthritis treatment postpones $75M IPO, raises $4M in debt instead

Palo Alto CA's Carbylan Therapeutics is developing a Phase III injectable combination therapy for knee osteoarthritis to compete with Sanofi's offering, but in a setback, its planned $75 million IPO was postponed.

AnaMar rethinks pipeline after analyzing ashes of failed trial

AnaMar has rejigged its pipeline priorities after digging through the data from its failed Phase IIa trial. The trial missed its primary endpoint of reducing pain in people with mild to moderate osteoarthritis pain, but a post hoc subgroup analysis has persuaded AnaMar it was trialling the right drug in the wrong indication.

Microcapsules shuttle promising protein to treat osteoarthritis

Building on years of research into the anti-inflammatory and tissue-repairing properties of the protein molecule C-type natriuretic peptide, investigators in the U.K. say they have managed to overcome one of the hurdles that has prevented its use for treating osteoarthritis.

Nexvet starts pivotal trial of pain-relieving antibody for arthritic dogs

Dublin-based Nexvet Biopharma has become the first company to launch a pivotal clinical trial of a monoclonal antibody (mAb) designed to combat pain in dogs with osteoarthritis.

Two new osteoarthritis biomarkers eyed for predictive Dx

U.K. researchers say they've zeroed in on two new biomarkers that could help predict who will develop osteoarthritis. The hope is that the biomarkers could form the basis of a blood test that enables earlier medical intervention before the condition causes too much damage.

Anika pops after the FDA finally approves its arthritis jab

After two stinging rejections sent it back to the lab, Anika Therapeutics has secured the FDA's blessing for an osteoarthritis pain injection, propelling the biotech's shares up more than 40%.

Merck KGaA scouts for deep-pocketed partners to leverage its R&D budget

The head of the pharma division, Stefan Oschmann, tells the Financial Times that the Darmstadt-based drug developer is looking to stretch its $1.5 billion annual research budget with some additional cost-sharing deals that might include private equity groups as well as other industry partners.