Kitov Pharma is looking to a Nasdaq IPO to fund the final steps in development of its osteoarthritis drug. The product, which is already deep into Phase III, is a combination of Pfizer's Celebrex and an antihypertensive drug, a mix Kitov thinks will enable it to avoid the black-box warnings that blight other treatments for osteoarthritis.
The Morris Animal Foundation has been tracking 3,000 golden retrievers since 2012, seeking information about common health conditions in dogs and how they're treated. One of the most widely reported problems in large-breed dogs is osteoarthritis, and now the foundation has gained some early insight into one of the most popular remedies sought out by dog owners to manage this painful condition: dietary supplements.
Xenon Pharmaceuticals' Teva-partnered treatment for osteoarthritis pain missed its goals in a Phase IIb trial, a failure the biotech believes won't derail the drug's development in other indications.
Moximed anticipates that its KineSpring System will prove useful for osteoarthritis sufferers as a first surgical step offered before arthroplasty. In support of its quest, the company has raised $33 million that it expects will be sufficient to gain FDA approval for the system.
Shares of Ampio Pharmaceuticals were crushed this morning after the biotech acknowledged that its lead drug flunked a Phase III test for osteoarthritis. And the news comes just days after one of its drug subsidiaries was absorbed into a new biotech that will be called Aytu.
Palo Alto CA's Carbylan Therapeutics is developing a Phase III injectable combination therapy for knee osteoarthritis to compete with Sanofi's offering, but in a setback, its planned $75 million IPO was postponed.
AnaMar has rejigged its pipeline priorities after digging through the data from its failed Phase IIa trial. The trial missed its primary endpoint of reducing pain in people with mild to moderate osteoarthritis pain, but a post hoc subgroup analysis has persuaded AnaMar it was trialling the right drug in the wrong indication.
Building on years of research into the anti-inflammatory and tissue-repairing properties of the protein molecule C-type natriuretic peptide, investigators in the U.K. say they have managed to overcome one of the hurdles that has prevented its use for treating osteoarthritis.
Dublin-based Nexvet Biopharma has become the first company to launch a pivotal clinical trial of a monoclonal antibody (mAb) designed to combat pain in dogs with osteoarthritis.
U.K. researchers say they've zeroed in on two new biomarkers that could help predict who will develop osteoarthritis. The hope is that the biomarkers could form the basis of a blood test that enables earlier medical intervention before the condition causes too much damage.