Tag:

depression

Latest Headlines

Latest Headlines

Pfizer preps its case for FDA pulling Chantix's black-box warning

The FDA polished up the official label on Pfizer's stop-smoking drug Chantix earlier this week. It was a victory for Pfizer, the payoff from several studies testing the drug for psychiatric side effects. Essentially, the new label will include study data suggesting that patients using the drug might not be at a greater risk of psychiatric problems after all.

Researchers develop the first blood test to diagnose adult depression

Researchers have identified 9 RNA blood markers that can be used as part of a panel to diagnose depression. They said it is the first blood test to diagnose adult depression.

Levels of small molecule in brain may indicate depression

A small molecule found in lower levels in the brains of people who are depressed may give scientists a better idea of how to treat patients with depression more effectively.

Naurex picks up $25M to get its depression drugs through PhII

Evanston, IL's Naurex nailed down another $25 million in venture funding to accelerate its two-pronged depression program, posting positive midstage results for its top prospect.

'Special K' once again wows investigators in small depression study

Yet another research team has pulled off a small study demonstrating the enormous potential of ketamine as a treatment for depression, highlighting again how difficult it has been to push beyond evidence of a rapid-acting treatment to develop a therapy with durable effects.

Party drug turned 'miracle' cure for depression spurs hype and stubborn hope

The notion that a party drug could be repurposed into a "miracle" cure for severe, treatment-resistant depression is an almost irresistible story line in the popular press. And there's no reason why it can't be recycled using results from the same small, short-duration study design that long ago attracted some of the world's largest research organizations still engaged in researching new drugs in one of the most difficult fields in R&D.

Cambridge U. researchers have discovered a biomarker for depression risk in boys

Cambridge University researchers and colleagues have identified an elegantly simple biomarker for major clinical depression in teenage boys: high levels of the stress hormone cortisol combined with behavioral symptoms.

J&J team marks another setback on depression as midstage study flops

J&J has come up empty-handed after wrapping a mid-stage study of an experimental anti-depressant. The pharma giant had in-licensed the drug from Addex Therapeutics, a Geneva-based biotech which reported that the program is being scrapped as investigators ponder possible alternative targets for ADX71149.

Gene biomarker may determine whether some depression drugs will work

Researchers have been unable to determine why some depression patients respond better than others to the class of drugs that includes Prozac, Zoloft and Celexa. Now a team has uncovered a gene that may act as a biomarker for this type of patient, potentially helping to match the drug with the patient.

Sage molecule could treat a wide range of CNS disorders

Scientists at the Cambridge, MA, startup Sage Therapeutics have discovered an innate mechanism that indirectly influences a key receptor linked to a number of neurologic and psychiatric disorders, including Alzheimer's, schizophrenia, autism and depression.